Use of ultrasound in the evaluation of trophoblastic disease and its response to therapy. [Comparison with HCG radioimmunoassay]
Thirty-nine patients with trophoblastic disease were studied to determine the usefulness of ultrasound in identifying risk patterns and response to therapy. Serial measurements of serum human chorionic gonadotropin-beta subunit (HCG-BSU) were compared with ultrasonographic uterine and theca lutein cyst volumes. In 16 patients ultrasound demonstrated theca lutein cysts, many of which were not palpable on physical examination. Although there was a significant decrease in uterine volume and a change in the sonographic pattern following evacuation, volume slowly returned to normal over a period of several months. Persistent trophoblastic disease was more accurately detected by HCG-BSU measurements than by ultrasound. Persistent disease developed in 44% of those patients who had theca lutein cysts and in 22% of those without cysts. Patients with theca lutein cysts did not consistently have higher HCG-BSU levels than patients without cysts, and it is concluded that ultrasound is the best method for detecting these cysts.
- Research Organization:
- Univ. of New Mexico, Albuquerque
- OSTI ID:
- 5301708
- Journal Information:
- Radiology; (United States), Vol. 135:2; Conference: 66. scientific assembly and annual meeting, Dallas, TX, USA, 16 Nov 1980
- Country of Publication:
- United States
- Language:
- English
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HCG
RADIOIMMUNOASSAY
DIAGNOSTIC USES
UROGENITAL SYSTEM DISEASES
DIAGNOSIS
UTERUS
ULTRASONOGRAPHY
IODINE 131
PATIENTS
WOMEN
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
FEMALE GENITALS
FEMALES
GONADOTROPINS
HORMONES
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
MAMMALS
MAN
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PEPTIDE HORMONES
PITUITARY HORMONES
PRIMATES
RADIOASSAY
RADIOISOTOPES
TRACER TECHNIQUES
USES
VERTEBRATES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
550600 - Medicine