Serum lipids in rats as related to modifications in dietary fat, fiber, and sodium with magnesium deficiency

Conference · Mon Mar 11 04:00:00 EST 1991 · FASEB Journal (Federation of American Societies for Experimental Biology); (United States)

OSTI ID:5301195

Howe, C A; Kubena, K S ^[1]

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1. Texas A and M Univ., College Station (United States)

Recommendations to modify dietary intake to attenuate risk of cardiovascular disease have been released by numerous governmental and health organizations. Since magnesium is associated with lipid metabolism and normal cardiovascular function, this study was designed to determine the effect of modifications in dietary fat, fiber, and sodium with magnesium deficiency on serum lipids and tissue minerals. The control (C) diet was based upon the AIN-76 diet formulation; the American (A) diet included average fat, fiber, and sodium levels in the US; and the recommended (R) diet was lower in fat and sodium and higher in fiber. Diets contained either 1,000 or 150 (L) mg Mg/kg diet. Male weanling Sprague-Dawley rats were fed one of the diets (C, CL, A, Al, R, RL) for six weeks. Levels of tissue Mg, Ca, Zn, and P were determined. Neither initial nor final body weights varied between groups. Serum levels of triglyceride were higher in the C and Cl groups than in the others. Serum cholesterol was lower in the R and Rl groups than in the Cl and A groups. Animals which were fed the diet modified with regard to fat, fiber, and sodium had lower serum cholesterol levels than did those fed the American diet. Magnesium deficiency was not consistently related to serum lipid levels.

• OSTI ID: 5301195
• Report Number(s): CONF-9104107--
• Conference Information: Journal Name: FASEB Journal (Federation of American Societies for Experimental Biology); (United States) Journal Volume: 5:4
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALI METALS
ALKALINE EARTH METALS
ANIMALS
BIOLOGICAL EFFECTS
CARDIOVASCULAR DISEASES
CHOLESTEROL
DIET
DISEASES
ELEMENTS
ESTERS
FATS
HYDROXY COMPOUNDS
LIPIDS
MAGNESIUM
MAMMALS
METABOLISM
METALS
MINERALS
NUTRITIONAL DEFICIENCY
ORGANIC COMPOUNDS
RATS
RODENTS
SODIUM
STEROIDS
STEROLS
TRIGLYCERIDES
VERTEBRATES