Toxicologic studies of SRC materials

Conference · Fri Feb 01 04:00:00 EST 1980

OSTI ID:5298640

Mahlum, D. D.; Pelroy, R. A.; Drucker, H.; Wilson, B. W.; Massey, M. J.; Schmalzer, D. K.

Investigations on the toxicity of SRC materials are reported. Toxicological studies include: microbial mutageneis (Ames test); in vitro mammalian cell toxicity and transformation assays; epidermal carcinogenesis (skin painting); acute and subchronic oral toxicity; developmental toxicity; dominant lethal assays; inhalation toxicity; and dosimetry and metabolism. The materials tested include: SRC-I process solvent, wash solvent, and light oil; SRC-II heavy distillate, middle distillate, and light distillate; shale oil; crude petroleum; and pure carcinogens. (DC)

• Research Organization: Battelle Pacific Northwest Labs., Richland, WA (USA); Environmental Research and Technology, Inc., Pittsburgh, PA (USA); Gulf Mineral Resources, Denver, CO (USA)
• DOE Contract Number: AC06-76RL01830
• OSTI ID: 5298640
• Report Number(s): PNL-SA-8439; CONF-800334-21
• Country of Publication: United States
• Language: English

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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
BIOASSAY
BIOLOGICAL EFFECTS
BODY
CARCINOGENESIS
CARCINOGENS
CELL CULTURES
COAL LIQUEFACTION
COMPARATIVE EVALUATIONS
DISPERSIONS
DISTILLATES
DOSIMETRY
ENERGY SOURCES
FOSSIL FUELS
FUELS
INHALATION
INTAKE
LIQUEFACTION
METABOLISM
MINERAL OILS
MIXTURES
MUTAGEN SCREENING
OILS
ORGANIC COMPOUNDS
ORGANS
OTHER ORGANIC COMPOUNDS
PATHOGENESIS
PETROLEUM
PROCESS SOLUTIONS
SCREENING
SHALE OIL
SKIN
SOLUTIONS
SRC PROCESS
SRC-II PROCESS
SYNTHETIC FUELS
SYNTHETIC PETROLEUM
THERMOCHEMICAL PROCESSES
TOXICITY