First-pass radionuclide angiography using a multiwire gamma camera and tantalum-178

Journal Article · Tue Mar 01 04:00:00 EST 1988 · J. Nucl. Med.; (United States)

OSTI ID:5294843

Lacy, J L; Verani, M S; Ball, M E; Boyce, T M; Gibson, R W; Roberts, R

A portable multiwire gamma camera (MWGC) with enhanced imaging characteristics relative to conventional sodium iodide camera has been evaluated with /sup 178/Ta, a short-lived, generator-produced radioisotope (half-life 9.3 min). First-pass radionuclide angiography (FPRA) was performed and results were compared to those obtained with FPRA using a multicrystal camera (MCC) and /sup 99m/Tc in 38 patients. The overall left ventricular count sensitivity (countsmCisecmillisteradians (msr)) was significantly higher with MWGC/sup 178/Ta (176 +- 132 versus 108 +- 49, p less than 0.001) yielding images of higher statistics with higher resolution collimation (31 versus 63 msr). Left ventricular ejection fraction was 0.54 +- 0.18 by MWGC and 0.54 +- 0.18 by MCC with an excellent correlation between the two techniques (r = 0.94, s.e.e. = 0.06). The detection of wall motion abnormality was virtually identical with the two techniques. Intra- and interobserver reproducibility by MWGC was excellent (r = 0.99 and 0.99, respectively). Thus, this new technology provides first-pass studies of higher statistical quality and improved resolution, affording more precise assessment of left ventricular performance and likelihood of further substantial improvement by use of even higher doses of /sup 178/Ta

• Research Organization: Baylor College of Medicine, Houston, TX (USA)
• OSTI ID: 5294843
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 29:3; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BIOLOGICAL HALF-LIFE
BIOMEDICAL RADIOGRAPHY
CAMERAS
DIAGNOSTIC TECHNIQUES
ELECTRON CAPTURE RADIOISOTOPES
GAMMA CAMERAS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
MINUTES LIVING RADIOISOTOPES
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
PATIENTS
RADIOISOTOPES
RADIOLOGY
SENSITIVITY ANALYSIS
TANTALUM 178
TANTALUM ISOTOPES
TECHNETIUM 99
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES