Microdosimetric analysis of proton RBE in diploid yeast cells at logarithmic stage of growth

Journal Article · Sat Jan 01 04:00:00 EST 1977 · Radiobiology (USSR) (Engl. Transl.); (United States)

OSTI ID:5276130

Videnskii, V G; Pitkevich, V A

On the assumption that the target of diploid yeast cells at the logarithmic stage of growth is the nucleus, in which there is homogeneous distribution of sensitive sites with linear size of the order of 1-10 nm, estimation was made of the probability of a different number of elementary physical lesions in the target as function of radiation dosage from protons varying in energy. From these data, survival curves and RBE as function of dosage were calculated. A comparison of calculated RBE as function of dosage to experimental functions made it possible to estimate the thickness of the sensitive site as 10 nm, mean ''distance'' between them as 60-80 nm and threshold energy of development of lesion as 1 keV.

• Research Organization: Scientific Research Inst. of Medical Radiology, Obninsk, USSR
• OSTI ID: 5276130
• Journal Information: Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 17:2; ISSN RADBA
• Country of Publication: United States
• Language: English

Related Subjects

560131* -- Radiation Effects on Microorganisms-- Basic Studies-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BARYONS
BIOMASS
CALCULATION METHODS
DATA ANALYSIS
DOSES
DOSIMETRY
ELEMENTARY PARTICLES
ENERGY SOURCES
FERMIONS
FUNGI
GROWTH
HADRONS
MICRODOSIMETRY
MICROORGANISMS
NUCLEONS
PLANTS
PROTONS
RADIATION DOSES
RBE
RENEWABLE ENERGY SOURCES
SIZE
SURVIVAL CURVES
YEASTS