Effects of three diets on mercury excretion after methylmercury administration

Journal Article · Tue May 01 04:00:00 EDT 1979 · Bull. Environ. Contam. Toxicol.; (United States)

DOI:https://doi.org/10.1007/BF02026922· OSTI ID:5274523

Landry, T D; Doherty, R A; Gates, A H

In mice it is suggested that dietary components may influence absorption and excretion of Hg compounds. This possibility was examined by determining the effects of (1) an evaporated whole milk diet, (2) a chemically defined liquid diet, and (3) a pelleted rodent diet on Hg retention in mice after administration of an apparently non-toxic dose of methylmercury (MeHg). Whole body Hg elimination and fecal and urinary Hg excretion were measured daily for two weeks. Two weeks after MeHg administration, Hg concentrations in whole body, brain, liver, kidney and whole blood were determined. The diet groups showed differences in whole body Hg retention and fecal Hg excretion.

• Research Organization: Univ. of Rochester, School of Medicine, NY
• OSTI ID: 5274523
• Journal Information: Bull. Environ. Contam. Toxicol.; (United States), Journal Name: Bull. Environ. Contam. Toxicol.; (United States) Vol. 22:1/2; ISSN BECTA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
CLEARANCE
DIET
ELEMENTS
EXCRETION
MAMMALS
MERCURY
MERCURY COMPOUNDS
METABOLISM
METALS
METHYLMERCURY
MICE
ORGANIC COMPOUNDS
ORGANIC MERCURY COMPOUNDS
PHYSIOLOGY
RODENTS
VERTEBRATES