c-fos and c-myc expression in human endothelial cells as a function of different culture conditions
Journal Article
·
· Experimental Cell Research; (United States)
- Instituto di Ricerche Farmacologiche Mario Negri, Milan (Italy)
Cultured human umbilical vein endothelial cells (HEC) could be induced to express c-fos and c-myc mRNA by either serum or ECGS (endothelial cell growth supplement). Neither agonist separately could support HEC proliferation but the combination did. Expression of c-fos and c-myc mRNA in the presence of both serum and ECGS was similar to that observed after each of the two stimuli was introduced separately. c-fos and c-myc expression in cultured HEC, even if related, is not necessarily accompanied by stimulation of cell growth.
- OSTI ID:
- 5269434
- Journal Information:
- Experimental Cell Research; (United States), Journal Name: Experimental Cell Research; (United States) Vol. 186:2; ISSN ECREA; ISSN 0014-4827
- Country of Publication:
- United States
- Language:
- English
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