Validation of attenuation-corrected equilibrium radionuclide angiographic determinations of right ventricular volume: comparison with cast-validated biplane cineventriculography

Journal Article · Thu Aug 01 04:00:00 EDT 1985 · Circulation; (United States)

DOI:https://doi.org/10.1161/01.CIR.72.2.317· OSTI ID:5246235

Dell'Italia, L J; Starling, M R; Walsh, R A; Badke, F R; Lasher, J C; Blumhardt, R

To determine the accuracy of attenuation-corrected equilibrium radionuclide angiographic determinations of right ventricular volumes, the authors initially studied 14 postmortem human right ventricular casts by water displacement and biplane cineventriculography. Biplane cineventriculographic right ventricular cast volumes, calculated by a modification of Simpson's rule algorithm, correlated well with right ventricular cast volumes measured by water displacement (r = .97, y = 8 + 0.88x, SEE = 6 ml). Moreover, the mean volumes obtained by both methods were no different (73 +/- 28 vs 73 +/- 25 ml). Subsequently, they studied 16 patients by both biplane cineventriculography and equilibrium radionuclide angiography. The uncorrected radionuclide right ventricular volumes were calculated by normalizing background corrected end-diastolic and end-systolic counts from hand-drawn regions of interest obtained by phase analysis for cardiac cycles processed, frame rate, and blood sample counts. Attenuation correction was performed by a simple geometric method. The attenuation-corrected radionuclide right ventricular end-diastolic volumes correlated with the cineventriculographic end-diastolic volumes (r = .91, y = 3 + 0.92x, SEE = 27 ml). Similarly, the attenuation-corrected radionuclide right ventricular end-systolic volumes correlated with the cineventriculographic end-systolic volumes (r = .93, y = - 1 + 0.91x, SEE = 16 ml). Also, the mean attenuation-corrected radionuclide end-diastolic and end-systolic volumes were no different than the average cineventriculographic end-diastolic and end-systolic volumes (160 +/- 61 and 83 +/- 44 vs 170 +/- 61 and 86 +/- 43 ml, respectively).

• Research Organization: Univ. of Texas Health Science Center, San Antonio
• OSTI ID: 5246235
• Journal Information: Circulation; (United States), Journal Name: Circulation; (United States) Vol. 2; ISSN CIRCA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BIOMEDICAL RADIOGRAPHY
BLOOD PRESSURE
BODY
CARDIOVASCULAR SYSTEM
COMPARATIVE EVALUATIONS
DIAGNOSTIC TECHNIQUES
ELEMENTS
HEART
MEDICINE
METALS
NUCLEAR MEDICINE
ORGANS
PATIENTS
RADIOLOGY
TECHNETIUM
TESTING
TRANSITION ELEMENTS
VALIDATION
VOLUME