Efficient stereospecific synthesis of no-carrier-added 2-(18F)-fluoro-2-deoxy-D-glucose using aminopolyether supported nucleophilic substitution
Journal Article
·
· J. Nucl. Med.; (United States)
OSTI ID:5239994
An aminopolyether mediated synthesis of fluorine-18 (18F) 2-fluoro-2-deoxy-D-glucose (FDG) has been developed. The nucleophilic fluorination with accelerator-produced (18F)fluoride works at the no-carrier-added level and gives epimerically pure 2-18FDG with an uncorrected radiochemical yield of a maximum 50% in a synthesis time of approximately 50 min from EOB.
- Research Organization:
- Institut fuer Chemie 1 (Nuklearchemie), Juelich, Germany, F.R.
- OSTI ID:
- 5239994
- Journal Information:
- J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 2; ISSN JNMEA
- Country of Publication:
- United States
- Language:
- English
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· J. Nucl. Med.; (United States)
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OSTI ID:6592002
Synthesis of no-carrier-added fluorine-18 2-fluoro-2-deoxy-d-glucose
Journal Article
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Mon Aug 01 00:00:00 EDT 1983
· J. Nucl. Med.; (United States)
·
OSTI ID:5748850
Related Subjects
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
400702* -- Radiochemistry & Nuclear Chemistry-- Properties of Radioactive Materials
ALDEHYDES
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
CARBOHYDRATES
CHEMICAL PREPARATION
CHEMICAL REACTIONS
CHEMISTRY
ETHERS
FLUORINATION
FLUORINE 18
FLUORINE ISOTOPES
GLUCOSE
HALOGENATION
HEXOSES
HOURS LIVING RADIOISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LABELLING
LIGHT NUCLEI
MONOSACCHARIDES
NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
POLYMERS
RADIOCHEMISTRY
RADIOISOTOPES
SACCHARIDES
SYNTHESIS
400702* -- Radiochemistry & Nuclear Chemistry-- Properties of Radioactive Materials
ALDEHYDES
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
CARBOHYDRATES
CHEMICAL PREPARATION
CHEMICAL REACTIONS
CHEMISTRY
ETHERS
FLUORINATION
FLUORINE 18
FLUORINE ISOTOPES
GLUCOSE
HALOGENATION
HEXOSES
HOURS LIVING RADIOISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LABELLING
LIGHT NUCLEI
MONOSACCHARIDES
NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
POLYMERS
RADIOCHEMISTRY
RADIOISOTOPES
SACCHARIDES
SYNTHESIS