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U.S. Department of Energy
Office of Scientific and Technical Information

Methods for evaluating the effects of environmental chemicals on human sperm production

Conference ·
OSTI ID:5237475
Sperm tests provide a direct and effective way of identifying chemical agents that induce spermatogenic damage in man. Four human sperm tests are available: sperm count, motility, morphology (seminal cytology), and the Y-body test. These sperm tests have numerous advantages over other approaches for assessing spermatogenic damage, and they have already been used to assess the effects of at least 85 different occupational, envionmental, and drug-related chemical exposures. When carefully controlled, seminal cytology appears to be statistically more sensitive than the other human sperm tests and should be considered an integral part of semen analysis when assessing induced spermatogenic damage.
Research Organization:
Lawrence Livermore National Lab., CA (USA)
DOE Contract Number:
W-7405-ENG-48
OSTI ID:
5237475
Report Number(s):
UCRL-87542; CONF-8110175-1; ON: DE82013789
Country of Publication:
United States
Language:
English