Localization error in the radiotherapy of Hodgkin's disease and malignant lymphoma with extended mantle fields. [99 lymphomas; 10 recurrent Hodgkins]

Conference · Mon Jul 01 04:00:00 EDT 1974 · Cancer; (United States)

OSTI ID:5237155

Marks, J E; Haus, A G; Sutton, H G; Griem, M L

In a review of 902 treatment verification films for 99 lymphoma patients receiving radiation therapy with extended mantle fields, 330 localization errors were detected. We found that 50 percent of the localization errors occurred in the axillae and that the axillae were the sites of most frequent clustering and recurrence. These facts suggest that localization errors caused sufficient reduction in dose to explain the recurrence of lymphoma in the axillae of several patients. Technical modifications of the blocks in relation to the axillae are discussed. Of 10 patients with local recurrence of Hodgkin's disease or malignant lymphoma, 2 had enough documented localization errors at the site of recurrence to account for a dose reduction sufficient to explain the recurrence. For the remaining 8 cases, we lacked sufficient films to determine the incidence of localization errors and thus to make estimates of reductions in dose. We observed a reduction of localization errors from 55 percent to 29 percent over the last 2 years of the study. This gratifying result is best explained by technical refinements and by the increased use of treatment verification films. On the basis of the data gathered in this study, we feel that treatment verification films are invaluable in the detection of localization errors in the treatment of lymphoma, and that they can lead to a reduction in localization errors if they are used regularly.

• OSTI ID: 5237155
• Conference Information: Journal Name: Cancer; (United States) Journal Volume: 34:1
• Country of Publication: United States
• Language: English

Related Subjects

560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL LOCALIZATION
DISEASES
DOCUMENT TYPES
ERRORS
HODGKINS DISEASE
IRRADIATION
LOCAL IRRADIATION
LYMPHOMAS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
RADIOLOGY
RADIOTHERAPY
REVIEWS
THERAPY