Lead poisoning in dogs: occurrence, source, clinical pathology, and electroencephalography

Journal Article · Mon May 01 04:00:00 EDT 1972 · Am. J. Vet. Res.; (United States)

OSTI ID:5225331

Zook, B C; Carpenter, J L; Roberts, R M

Accidental lead poisoning was diagnosed and studied in 236 dogs. The disease incidence increased annually after 1963 and was more common in Poodles and dogs less than 1 year old. The incidence was greatest in summer and early fall and was more common in dogs which dwelt in slum areas than was expected. Lead-based paints were the most frequent source of poisoning. Results of hematologic and urinary determinations supported those of previous studies. The diagnostic importance of nucleated and stippled red blood cells (RBC) in peripheral blood films was emphasized, and urine sediments frequently contained casts with few inflammatory cells. In addition, reticulocyte counts were usually increased and sedimentation rates and Coomb's test results were normal. Results of bone marrow studies indicated hyperplasia of, and partial maturation defect in, the erythrocytic series of most dogs. Determinations of various clinical chemistry tests and cerebrospinal fluid analysis were usually normal. Electroencephalographic changes consisted of irregular, generalized slow-wave activity of increased amplitude. 20 references, 5 figures, 12 tables.

• Research Organization: George Washington Univ., Washington, DC
• OSTI ID: 5225331
• Journal Information: Am. J. Vet. Res.; (United States), Journal Name: Am. J. Vet. Res.; (United States) Vol. 33:5; ISSN AJVRA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AGE DEPENDENCE
ANIMAL TISSUES
ANIMALS
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BLOOD
BODY
BODY FLUIDS
BONE MARROW
CEREBROSPINAL FLUID
CHEMICAL ANALYSIS
COATINGS
DIAGNOSTIC TECHNIQUES
DISEASE INCIDENCE
DISTRIBUTION
DOGS
ELECTROENCEPHALOGRAPHY
ELEMENTS
HEMATOPOIETIC SYSTEM
INJURIES
LEAD
MAMMALS
MATERIALS
METALS
ORGANS
PAINTS
SEASONAL VARIATIONS
TISSUE DISTRIBUTION
TISSUES
TOXICITY
URINE
VARIATIONS
VERTEBRATES
WASTES