Bone and bone-marrow blood flow in chronic granulocytic leukemia and primary myelofibrosis

Journal Article · Mon Mar 01 04:00:00 EST 1982 · J. Nucl. Med.; (United States)

OSTI ID:5211071

Lahtinen, R; Lahtinen, T; Romppanen, T

Blood flow in hematopoietic bone marrow and in nonhematopoietic bone has been measured with a Xe-133 washout method in 20 patients with chronic granulocytic leukemia (CGL) and in seven with primary myelofibrosis. Age-matched healthy persons served as controls. Bone-marrow blood flow in CGL was dependent upon the phase of the disease. In the metamorphosis phase, bone-marrow blood flow was high compared with that in the well-controlled phase. Apart from the initial phase, the mean values for bone blood flow in CGL were increased compared with the values of the healthy controls. In myelofibrosis the bone blood flow was also increased. Bone-marrow blood flow in these diseases was dependent upon the cellularity of bone marrow as measured morphometrically.

• Research Organization: Kuopio University Central Hospital, Finland
• OSTI ID: 5211071
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 23:3; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMAL TISSUES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BLOOD FLOW
BODY
BONE MARROW
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DISEASES
EVEN-ODD NUCLEI
FIBROSIS
HEMATOPOIETIC SYSTEM
HEMIC DISEASES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LEUKEMIA
NEOPLASMS
NUCLEI
ORGANS
PATHOLOGICAL CHANGES
PATHOLOGY
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
TISSUES
XENON 133
XENON ISOTOPES