Ultrastructure of the liver cell in subacute manganese administration
Journal Article
·
· Environ. Res.; (United States)
Ultrastructural changes of the liver cell in rats which received in their drinking water an extra dosage of 200 ppM manganese chloride during 10 weeks are reported. These changes consist of an increased amount of rough endoplasmic reticulum, a proliferated smooth endoplasmic reticulum in the centrolobular area, prominent Golgi apparatuses in the biliary area, polymorphous mitochondria with electron dense matrices and the occurrence of multiple rough endoplasmic cisternae. They suggest a state of heterostasis of the liver cell as an expression of the adaptation process to increased exposure to manganese chloride.
- Research Organization:
- Hebrew Univ.-Hadassah Medical School, Jerusalem
- OSTI ID:
- 5204441
- Journal Information:
- Environ. Res.; (United States), Journal Name: Environ. Res.; (United States) Vol. 14:3; ISSN ENVRA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550300 -- Cytology
560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BODY
CELL CONSTITUENTS
CHLORIDES
CHLORINE COMPOUNDS
DIGESTIVE SYSTEM
DRINKING WATER
ENDOPLASMIC RETICULUM
GLANDS
HALIDES
HALOGEN COMPOUNDS
HYDROGEN COMPOUNDS
LIVER
MAMMALS
MANGANESE CHLORIDES
MANGANESE COMPOUNDS
MANGANESE HALIDES
MITOCHONDRIA
MORPHOLOGICAL CHANGES
ORAL ADMINISTRATION
ORGANOIDS
ORGANS
OXYGEN COMPOUNDS
RATS
RODENTS
TRANSITION ELEMENT COMPOUNDS
ULTRASTRUCTURAL CHANGES
VERTEBRATES
WATER
560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BODY
CELL CONSTITUENTS
CHLORIDES
CHLORINE COMPOUNDS
DIGESTIVE SYSTEM
DRINKING WATER
ENDOPLASMIC RETICULUM
GLANDS
HALIDES
HALOGEN COMPOUNDS
HYDROGEN COMPOUNDS
LIVER
MAMMALS
MANGANESE CHLORIDES
MANGANESE COMPOUNDS
MANGANESE HALIDES
MITOCHONDRIA
MORPHOLOGICAL CHANGES
ORAL ADMINISTRATION
ORGANOIDS
ORGANS
OXYGEN COMPOUNDS
RATS
RODENTS
TRANSITION ELEMENT COMPOUNDS
ULTRASTRUCTURAL CHANGES
VERTEBRATES
WATER