Bullous pemphigoid after radiation therapy

Journal Article · Mon Feb 01 00:00:00 EST 1988 · J. Am. Acad. Dermatol.; (United States)

DOI:https://doi.org/10.1016/S0190-9622(88)70066-3· OSTI ID:5198841

Duschet, P; Schwarz, T; Gschnait, F

Electron beam therapy applied to a lymph node metastasis from a squamous cell carcinoma was followed by the development of histologically and immunologically typical bullous pemphigoid, the lesions being initially strictly confined to the irradiation area. This observation suggests that the bullous pemphigoid antigen may be altered or unmasked by electron beam radiotherapy, leading subsequently to the production of autoantibodies. The disease in this case effectively responded to the administration of tetracycline and niacinamide, a therapeutic regimen described recently.

• Research Organization: Hospital Vienna-Lainz (Austria)
• OSTI ID: 5198841
• Journal Information: J. Am. Acad. Dermatol.; (United States), Vol. 18
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CARCINOMAS
RADIOTHERAPY
RADIODERMATITIS
RADIOINDUCTION
SIDE EFFECTS
BIOLOGICAL RADIATION EFFECTS
ELECTRON BEAMS
LYMPH NODES
METASTASES
NICOTINAMIDE
AMIDES
AZINES
BEAMS
BIOLOGICAL EFFECTS
DERMATITIS
DISEASES
HETEROCYCLIC COMPOUNDS
INJURIES
LEPTON BEAMS
LOCAL RADIATION EFFECTS
LYMPHATIC SYSTEM
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PARTICLE BEAMS
PYRIDINES
RADIATION EFFECTS
RADIATION INJURIES
RADIOLOGY
SKIN DISEASES
THERAPY
VITAMIN B GROUP
VITAMINS
560151* - Radiation Effects on Animals- Man