Medulloblastoma: Long-term follow-up of patients treated with electron irradiation of the spinal field

Journal Article · Sun Sep 01 00:00:00 EDT 1991 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.180.3.1871308· OSTI ID:5187594

Gaspar, L E; Dawson, D J; Tilley-Gulliford, S A; Banerjee, P ^[1]

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1. London Regional Cancer Centre, Ontario (Canada)

Thirty-two patients with posterior fossa medulloblastoma underwent treatment with electron irradiation to the spinal field. The 5- and 10-year actuarial survival rates were 57% and 50%, respectively. Late complications observed in the 15 patients followed up for more than 5 years were short stature (six patients), decreased sitting-standing height ratio (four patients), scoliosis (two patients), poor school performance (seven patients), xerostomia (one patient), esophageal stricture (one patient), pituitary dysfunction (four patients), primary hypothyroidism (one patient), bilateral eighth-nerve deafness (one patient), and carcinoma of the thyroid (one patient). Complications following treatment with electrons to a spinal field are compared with reported complications following treatment with photons to the spinal field. Although short-term reactions were minimal, the authors found no difference in late complications. More sophisticated treatment planning may show such a long-term benefit in the future.

• OSTI ID: 5187594
• Journal Information: Radiology; (United States), Vol. 180:3; ISSN 0033-8419
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
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SIDE EFFECTS
DELAYED RADIATION EFFECTS
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ORGANS
RADIATION EFFECTS
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