Regional Stage IV carcinoma of the nasopharynx treated by aggressive radiotherapy

Journal Article · Tue Nov 01 04:00:00 EST 1983 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(83)90428-5· OSTI ID:5177902

Cooper, J S; del Roew, J; Newall, J

Between January 1, 1969 and December 31, 1981, 45 patients received radiotherapy for advanced (Stage IV) carcinoma of the nasopharynx confined to the head and neck at New York University Medical Center. Forty of these 45 patients received at least 6000 cGy. The 5 and 10 year actuarial survival rates were 31 and 20%. Four patients are currently alive without evidence of disease at least 10 years after treatment. Local persistence or recurrence of tumor in the nasopharynx was the primary cause of failure and occurred in 42% of our patients. The likelihood of this type of treatment failure correlated with the initial T stage of disease. Inability to control nodal disease was less common, occurring in 23% of evaluable patients and was proportional to the N stage. Distant metastases became apparent in 13% of our patients and correlated with the N stage. More than 90% of recurrences were evident within two and all occurred within three years of treatment.

• Research Organization: New York Univ., NY
• OSTI ID: 5177902
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 9:11; ISSN IOBPD
• Country of Publication: United States
• Language: English

Related Subjects

550602 -- Medicine-- External Radiation in Diagnostics-- (1980-)
550603* -- Medicine-- External Radiation in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
BODY AREAS
CARCINOMAS
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
ELECTROMAGNETIC RADIATION
ENERGY RANGE
EVALUATION
HARD X RADIATION
HEAD
IONIZING RADIATIONS
MEDICINE
MEV RANGE
MEV RANGE 01-10
NECK
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
PHARYNX
RADIATIONS
RADIOLOGY
RADIOTHERAPY
RESPIRATORY SYSTEM
THERAPY
TOMOGRAPHY
X RADIATION