Metabolism of naphthalene by Cunninghamella elegans

Journal Article · Sat Oct 01 04:00:00 EDT 1977 · Appl. Environ. Microbiol.; (United States)

OSTI ID:5166103

Cerniglia, C E; Gibson, D T

Cunninghamella elegans grown on Sabouraud dextrose broth in the presence of naphthalene produced six metabolites. Each product was isolated and identified by conventional chemical technique. The major metabolites were 1-naphthol (67.9 percent) and 4-hydroxy-1-tetralone (16.7 percent). Minor products isolated were 1,4-naphthoquinone (2.8 percent), 1,2-naphthoquinone (0.2 percent), 2-naphthol (6.3 percent), and trans-1,2-dihydroxy-1,2-dihydronaphthalene (5.3 percent). C. elegans oxidized both 1-naphthol and 1,4-naphthoquinone to 4-hydroxy-1-tetralone. The results suggest that C. elegans oxidizes naphthalene by a sequence of reactions similar to those reported for the mammalian metabolism of this hydrocarbon.

• Research Organization: Univ. of Texas, Austin
• OSTI ID: 5166103
• Journal Information: Appl. Environ. Microbiol.; (United States), Journal Name: Appl. Environ. Microbiol.; (United States) Vol. 34:4; ISSN AEMID
• Country of Publication: United States
• Language: English

Related Subjects

550500 -- Metabolism
560302* -- Chemicals Metabolism & Toxicology-- Microorganisms-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
AROMATICS
BACTERIA
BIOCHEMICAL REACTION KINETICS
BIODEGRADATION
CHEMICAL REACTIONS
CONDENSED AROMATICS
DECOMPOSITION
HYDROCARBONS
KINETICS
MAMMALS
METABOLISM
METABOLITES
MICROORGANISMS
NAPHTHALENE
ORGANIC COMPOUNDS
REACTION KINETICS
VERTEBRATES