Determination of the specific activity of high specific activity tritium labeled sodium borohydride by tritium nuclear magnetic resonance spectrometry

Journal Article · Thu May 01 04:00:00 EDT 1980 · Anal. Chem.; (United States)

DOI:https://doi.org/10.1021/ac50056a053· OSTI ID:5162977

Altman, L ^[1]; Thomas, L

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1. State Univ. of New York, Stony Brook

A rapid, nondestructive method for the determination of the specific activity of high specific activity borohydrides based on tritium nuclear magnetic resonance spectroscopy is reported. NMR spectra were measured utilizing a Bruker WP-200 spectrometer equipped with a separate probe for observation of tritium NMR spectra. The 200 MH/sub 2/ /sup 1/H NMR spectrum of sodium borohydride in basic CD/sub 3/OD is given. The proton decoupled 213.4 MHz /sup 3/H NMR spectrum of labeled sodium borohydride is included. Four quartets are immediately apparent - one for each isotopically distinct species Na/sup 11/BH/sub 4-n/Tn- as well as two septets - one each for Na/sup 10/BH/sub 2/T/sub 2/ and Na /sup 10/BHT/sub 3/. Since each isotopomer gives rise to separate NMR signals, it appears possible to determine the mole percent of each isotopomer by integrating the individual signals. Using tritium NMR acquistion conditions designed to minimize the effects of differential relaxation, the specific activity of labeled sodium borohydride can be determined by acquisition of both the proton decoupled tritium NMR spectrum in order to determine the isotopomer distribution among tritiated molecules and the /sup 1/H NMR spectrum in order to determine the percent of unlabeled borohydride. 5 figures, 3 tables. (DP)

• OSTI ID: 5162977
• Journal Information: Anal. Chem.; (United States), Journal Name: Anal. Chem.; (United States) Vol. 52:6; ISSN ANCHA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400104* -- Spectral Procedures-- (-1987)
ALKALI METAL COMPOUNDS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BOROHYDRIDES
BORON COMPOUNDS
HYDROGEN COMPOUNDS
HYDROGEN ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LIGHT NUCLEI
MAGNETIC RESONANCE
NUCLEAR MAGNETIC RESONANCE
NUCLEI
ODD-EVEN NUCLEI
RADIOACTIVITY
RADIOISOTOPES
RESONANCE
SODIUM COMPOUNDS
SPECIFICITY
TRITIUM
TRITIUM COMPOUNDS
YEARS LIVING RADIOISOTOPES