Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals

Journal Article · Wed Jan 01 00:00:00 EST 1986 · Environ. Mutagen.; (United States)

DOI:https://doi.org/10.1002/em.2860080802· OSTI ID:5148494

Mortelmans, K; Haworth, S; Lawlor, T; Speck, W; Tainer, B; Zeiger, E

This publication includes data of Salmonella mutagenicity results on 270 coded chemicals, encompassing 329 tests performed by three laboratories under contract to the National Toxicology Program (NTP). The preincubation modification of the Salmonella/mammalian microsome assay was used to test chemicals in up to five Salmonella strains in the presence and absence of rat and hamster liver S-9. With a few exceptions, inter- and intralaboratory reproducibility was good.

• Research Organization: SRI International, Menlo Park, CA
• OSTI ID: 5148494
• Journal Information: Environ. Mutagen.; (United States), Vol. 8:7
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CARCINOGENS
MUTAGEN SCREENING
MUTAGENESIS
RISK ASSESSMENT
MUTAGENS
CHLORINATED AROMATIC HYDROCARBONS
MICROSOMES
MUTATION FREQUENCY
POLYCYCLIC AROMATIC HYDROCARBONS
SALMONELLA TYPHIMURIUM
AROMATICS
BACTERIA
CELL CONSTITUENTS
HALOGENATED AROMATIC HYDROCARBONS
HYDROCARBONS
MICROORGANISMS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANOIDS
SALMONELLA
SCREENING
560302* - Chemicals Metabolism & Toxicology- Microorganisms- (-1987)