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Effects of. gamma. irradiation on the hydration characteristics of DNA and polynucleotides. II. An NMR study of mixed H/sub 2/O/D/sub 2/O frozen solutions

Journal Article · · Radiat. Res.; (United States)
OSTI ID:5144179
The effects of ..gamma.. irradiation at different temperatures on the hydration water proton resonance spectra from frozen H/sub 2/O/D/sub 2/O solutions of DNA and polynucleotides were studied. Comparison of results obtained with pure H/sub 2/O solutions showed a striking difference in the temperature-dependent variations of ..delta../sub /sup 1///sub 2// values in nonirradiated and irradiated DNA solutions. There is evidence that base rehydration with hydration water molecules occurs after an initial damage to the macromolecular chains in DNA caused by the direct or indirect radiation effects.
Research Organization:
Univ. Libre de Bruxelles, Belgium
OSTI ID:
5144179
Journal Information:
Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 72; ISSN RAREA
Country of Publication:
United States
Language:
English