Adjustment of urinary concentration to urinary volume in relation to erythrocyte and plasma concentrations: an evaluation of urinary heavy metals and organic substances

Journal Article · Thu May 01 04:00:00 EDT 1986 · Arch. Environ. Health; (United States)

DOI:https://doi.org/10.1080/00039896.1986.9935773· OSTI ID:5142238

Araki, S; Aono, H; Murata, K

The effects of urinary volume on adjusted and nonadjusted urinary excretion of 11 heavy metals and organic substances were examined in relation to plasma and erythrocyte concentrations in 19 metal workers under conditions of water restriction and loading. Blood lead concentrations in these workers ranged from 25 to 59 micrograms/dl. The results indicated that: urinary volume significantly affects not only nonadjusted urinary concentration for all substances, but also affects timed excretion and concentrations adjusted to urinary specific gravity and to urinary creatinine for most substances; the concentration adjusted to urinary volume is, on the other hand, independent of urinary volume; and urinary excretion of lead and mercury is related more closely to erythrocyte concentration than to plasma concentration. This last finding reflects complex renal excretory mechanisms for these heavy metals.

• Research Organization: Medical College of Oita, Japan
• OSTI ID: 5142238
• Journal Information: Arch. Environ. Health; (United States), Journal Name: Arch. Environ. Health; (United States) Vol. 3; ISSN AEHLA
• Country of Publication: United States
• Language: English

Related Subjects

560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BLOOD
BLOOD CELLS
BODY FLUIDS
CLEARANCE
ELEMENTS
ERYTHROCYTES
EXCRETION
HYDROGEN COMPOUNDS
INDUSTRY
LEAD
MATERIALS
MERCURY
METAL INDUSTRY
METALS
OCCUPATIONAL EXPOSURE
OXYGEN COMPOUNDS
PERSONNEL
URINE
VOLUME
WASTES
WATER