Radiochemical changes in phosphatidyl choline

Journal Article · Sat Jan 01 04:00:00 EST 1977 · Radiobiology (USSR) (Engl. Transl.); (United States)

OSTI ID:5141802

Mochalina, A S; Klimova, T P

Radiolytic oxidation of phosphatidyl choline leads to production of a mixture of products with various physicochemical properties. Appearance of conjugated hydroperoxides with a typical absorption band at 232 nm and unsaturated carbonyl compounds with absorption at 270 to 280 nm and reacting with 2-thiobarbituric acid is indicative of radiation injury to the fatty acid part of phospholipid. Exposure of phosphatidyl choline to radiation elicits a break in the phosphoether bond with splitting of phosphate, the radiochemical yield of which constitutes 0.4 molecule per 100 eV.

• OSTI ID: 5141802
• Journal Information: Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 17:5; ISSN RADBA
• Country of Publication: United States
• Language: English

Related Subjects

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
400600* -- Radiation Chemistry
ALCOHOLS
AMINES
AMMONIUM COMPOUNDS
CARBONYLS
CHEMICAL RADIATION EFFECTS
CHEMICAL REACTIONS
CHEMISTRY
CHOLINE
DECOMPOSITION
ESTERS
HYDROGEN COMPOUNDS
HYDROGEN PEROXIDE
HYDROXY COMPOUNDS
LIPIDS
LIPOTROPIC FACTORS
ORGANIC COMPOUNDS
ORGANIC PHOSPHORUS COMPOUNDS
OXIDATION
OXYGEN COMPOUNDS
PEROXIDES
PHOSPHOLIPIDS
QUATERNARY COMPOUNDS
RADIATION CHEMISTRY
RADIATION EFFECTS
RADIOLYSIS