Comparative evaluation of fatty acids labeled with C-11 CI-34m, Br-77, and I-123 for metabolic studies of the myocardium; concise communication. [Mice]
Journal Article
·
· J. Nucl. Med.; (United States)
OSTI ID:5111192
Various long-chain fatty acids have been labeled with C-11, Cl-34m, Br-77, and I-123 and evaluated for their potential application in measuring myocardial metabolism in vivo. Comparative studies of the kinetics of accumulation and clearance from the heart muscle of mice indicate that the extraction of ..omega..-halofatty acids is more efficient than that of ..cap alpha..-halofatty acids. Among the ..omega..-halofatty acids, the highest uptake is observed for the 17-iodoheptadecanoic acid, which shows an extraction behavior almost identical to that of (I-/sup 11/C) palmitic acid, although with a higher radioactivity level in blood due to the release of free iodide.
- Research Organization:
- Kernforschungsanlage, Julich, Ger.
- OSTI ID:
- 5111192
- Journal Information:
- J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 19:3; ISSN JNMEA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Assessment of myocardial metabolism with iodine-123 heptadecanoic acid: effect of decreased fatty acid oxidation on deiodination
Quantitation of myocardial fatty acid metabolism using PET
I-123 labeled radiotracers in cardiovascular nuclear medicine
Journal Article
·
Wed Jun 01 00:00:00 EDT 1988
· J. Nucl. Med.; (United States)
·
OSTI ID:6859075
Quantitation of myocardial fatty acid metabolism using PET
Journal Article
·
Tue Oct 01 00:00:00 EDT 1996
· Journal of Nuclear Medicine
·
OSTI ID:478529
I-123 labeled radiotracers in cardiovascular nuclear medicine
Journal Article
·
Thu Mar 31 23:00:00 EST 1983
· IEEE Trans. Nucl. Sci.; (United States)
·
OSTI ID:5606136
Related Subjects
560172* -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Animals-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BODY
BROMINE 77
BROMINE ISOTOPES
CARBON 11
CARBON ISOTOPES
CARBOXYLIC ACIDS
CARDIOVASCULAR SYSTEM
CHLORINE 34
CHLORINE ISOTOPES
DAYS LIVING RADIOISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
HEART
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE 123
IODINE ISOTOPES
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLING
LIGHT NUCLEI
MAMMALS
MEASURING METHODS
METABOLISM
MICE
MINUTES LIVING RADIOISOTOPES
MUSCLES
MYOCARDIUM
NUCLEI
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
RADIOISOTOPES
RADIONUCLIDE KINETICS
RODENTS
SECONDS LIVING RADIOISOTOPES
VERTEBRATES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BODY
BROMINE 77
BROMINE ISOTOPES
CARBON 11
CARBON ISOTOPES
CARBOXYLIC ACIDS
CARDIOVASCULAR SYSTEM
CHLORINE 34
CHLORINE ISOTOPES
DAYS LIVING RADIOISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
HEART
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE 123
IODINE ISOTOPES
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLING
LIGHT NUCLEI
MAMMALS
MEASURING METHODS
METABOLISM
MICE
MINUTES LIVING RADIOISOTOPES
MUSCLES
MYOCARDIUM
NUCLEI
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
RADIOISOTOPES
RADIONUCLIDE KINETICS
RODENTS
SECONDS LIVING RADIOISOTOPES
VERTEBRATES