Structural changes in myelokaryocyte chromosomes at the late postradiation stage in DNA-treated rats. [Gamma radiation]
Journal Article
·
· Radiobiology (USSR) (Engl. Transl.); (United States)
OSTI ID:5111036
Rats were exposed to 840 R of gamma radiation and 24 h later homologous or heterologous DNA was given to the exerimental group. The animals were killed at intervals up to 18 months later and cytological preparations were made from bone marrow. The bone marrow of rats treated with DNA did not show significant differences in polyploidy or aneuploidy as compared to untreated rats. However, the percentage of chromosomal aberrations was significantly lower in rats treated with DNA. The relationship of chromosomal aberrations to severity of pathological changes in hematopoietic tissues is discussed. (HLW)
- OSTI ID:
- 5111036
- Journal Information:
- Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 17:4; ISSN RADBA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANEUPLOIDY
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BONE MARROW CELLS
CHROMOSOMAL ABERRATIONS
CONNECTIVE TISSUE CELLS
DNA
ELECTROMAGNETIC RADIATION
GAMMA RADIATION
IONIZING RADIATIONS
MAMMALS
MUTATIONS
NUCLEIC ACIDS
ORGANIC COMPOUNDS
PLOIDY
POLYPLOIDY
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
RADIOSENSITIVITY EFFECTS
RATS
RODENTS
SOMATIC CELLS
VERTEBRATES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANEUPLOIDY
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BONE MARROW CELLS
CHROMOSOMAL ABERRATIONS
CONNECTIVE TISSUE CELLS
DNA
ELECTROMAGNETIC RADIATION
GAMMA RADIATION
IONIZING RADIATIONS
MAMMALS
MUTATIONS
NUCLEIC ACIDS
ORGANIC COMPOUNDS
PLOIDY
POLYPLOIDY
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
RADIOSENSITIVITY EFFECTS
RATS
RODENTS
SOMATIC CELLS
VERTEBRATES