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Renography with captopril. Changes in a patient with hypertension and unilateral renal artery stenosis

Journal Article · · Arch. Intern. Med.; (United States)
; ; ;
In a 56-year-old man with severe familial hypertension and unilateral renal artery stenosis, captopril induced striking changes in the renograms of the affected kidney. After injection of orthoiodohippurate sodium I 131, the uptake phase was unchanged but the later curve showed continuous accumulation. In contrast, the uptake of technetium Tc 99m diethylenetriamine pentracetic acid was abolished. These changes are compatible with a cessation of filtration and maintenance of renal blood flow. After balloon dilatation of the stenosis, the blood pressure became lower, and these changes could no longer be demonstrated. The captopril renogram may provide useful information on the dependency of hypertension on unilateral renal artery stenosis.
Research Organization:
Univ. Hospital, Utrecht, the Netherlands
OSTI ID:
5072920
Journal Information:
Arch. Intern. Med.; (United States), Journal Name: Arch. Intern. Med.; (United States) Vol. 9; ISSN AIMDA
Country of Publication:
United States
Language:
English

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Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AMINO ACIDS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOMEDICAL RADIOGRAPHY
BODY
CARBOXYLIC ACIDS
CARDIOVASCULAR DISEASES
CHELATING AGENTS
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
DTPA
HOURS LIVING RADIOISOTOPES
HYPERTENSION
INTERMEDIATE MASS NUCLEI
IODINE 131
IODINE ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
KIDNEYS
MEDICINE
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
PATIENTS
RADIOISOTOPES
RADIOLOGY
RADIOPROTECTIVE SUBSTANCES
RENOGRAPHY
RESPONSE MODIFYING FACTORS
SYMPTOMS
TECHNETIUM 99
TECHNETIUM ISOTOPES
UPTAKE
VASCULAR DISEASES
YEARS LIVING RADIOISOTOPES