HPLC determination of tocopherol, retinol, dehydroretinol and retinyl palmitate in tissues of Lake Char (Salvelinus namaycush) exposed to coplanar 3,3[prime],4,4[prime],5-pentachlorobiphenyl

Journal Article · Tue Mar 01 04:00:00 EST 1994 · Environmental Toxicology and Chemistry; (United States)

DOI:https://doi.org/10.1897/1552-8618(1994)13[473:HDOTRD]2.0.CO;2· OSTI ID:5024402

Palace, V P ^[1]; Brown, S B ^[2]

---

1. Univ. of Manitoba, Winnipeg, Manitoba (Canada). Dept. of Zoology
2. Univ. of Manitoba, Winnipeg, Manitoba (Canada). Dept. of Fisheries and Oceans

Tocopherol, retinol, dehydroretinol, and retinyl palmitate were measured by reversed-phase HPLC in liver, kidney, and plasma of lake char exposed to orally administered coplanar 3,3[prime],4,4[prime],5-pentachlorobiphenyl (PCB). Tocopherol concentrations were unaffected after eight weeks. Liver retinol, dehydroretinol, and retinyl palmitate concentrations were lower, whereas kidney retinyl palmitate was elevated in PCB-exposed groups. Tissue retinoid concentrations provide sensitive indicators of coplanar PCB exposure in fish.

• OSTI ID: 5024402
• Journal Information: Environmental Toxicology and Chemistry; (United States), Journal Name: Environmental Toxicology and Chemistry; (United States) Vol. 13:3; ISSN 0730-7268; ISSN ETOCDK
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
AQUATIC ORGANISMS
AROMATICS
BIOLOGICAL EFFECTS
CHLORINATED AROMATIC HYDROCARBONS
CHROMATOGRAPHY
FISHES
HALOGENATED AROMATIC HYDROCARBONS
LIQUID COLUMN CHROMATOGRAPHY
METABOLISM
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
POLYCHLORINATED BIPHENYLS
SENSITIVITY
SEPARATION PROCESSES
VERTEBRATES
VITAMIN A
VITAMIN E
VITAMINS