Mercuric- and mercurial-resistance determined by R factors in Escherichia coli

Journal Article · Tue Jan 01 04:00:00 EST 1974 · Am Soc Microbiol annu meet abstr; (United States)

OSTI ID:5018479

Boedges, J; Mandal, A

Resistance to mercuric chloride and phenylmercuric acetate (PMA) was tested by disc inhibition tests with 24 known E. coli strains harboring R factors and 126 new clinical isolates of E. coli. Of these 150 strains, 17 were resistant only to HgCl/sub 2/, 7 were resistant only to PMA, and 4 were resistant to both HgCl/sub 2/ and PMA. 20 of the 28 strains resistant to HgCl/sub 2/ and/or PMA showed resistance also to 2 or more of 8 antibiotics tested; however, 7 of the remaining 8 strains did not show resistance to any tested antibiotic. 24 of the 44 multiple antibiotic resistance strains showed no resistance to HgCl/sub 2/ or PMA. /sup 203/Hg(II) studies showed mercuric resistance to be associated with reduction of Hg(II) ..-->.. Hg(0) and volatilization of metallic mercury from the medium. /sup 203/Hg-PMA was not volatilized under the conditions of inorganic /sup 203/Hg(II) volatilization.

• Research Organization: Washington Univ., St. Louis, MO
• OSTI ID: 5018479
• Journal Information: Am Soc Microbiol annu meet abstr; (United States), Journal Name: Am Soc Microbiol annu meet abstr; (United States)
• Country of Publication: United States
• Language: English

Related Subjects

550700 -- Microbiology
560302* -- Chemicals Metabolism & Toxicology-- Microorganisms-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANTI-INFECTIVE AGENTS
ANTIBIOTICS
BACTERIA
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
CHLORIDES
CHLORINE COMPOUNDS
COMPARATIVE EVALUATIONS
DAYS LIVING RADIOISOTOPES
DRUGS
ESCHERICHIA COLI
EVAPORATION
EVEN-ODD NUCLEI
HALIDES
HALOGEN COMPOUNDS
HEAVY NUCLEI
ISOTOPE APPLICATIONS
ISOTOPES
MERCURY 203
MERCURY CHLORIDES
MERCURY COMPOUNDS
MERCURY HALIDES
MERCURY ISOTOPES
MICROORGANISMS
NUCLEI
ORGANIC COMPOUNDS
ORGANIC MERCURY COMPOUNDS
PHASE TRANSFORMATIONS
RADIOISOTOPES
TOLERANCE
TRACER TECHNIQUES