Human endopeptidase (THOP1) is localized on chromosome 19 within the linkage region for the late-onset Alzheimer disease AD2 locus
- Boston Univ. School of Medicine, MA (United States)
- Duke Univ. Medical Center, Durham, NC (United States); and others
A cDNA encoding the rat endopeptidase 24.15 was used to determine the chromosomal localization of the respective human gene. Hybridization to DNA from human-rodent somatic cell hybrids assigned the human gene to chromosome 19. Fluorescence in situ hybridization on human metaphase chromosomes localized the human endopeptidase 24.15 to 19q13.3. 27 refs., 1 fig., 1 tab.
- OSTI ID:
- 501826
- Journal Information:
- Genomics, Journal Name: Genomics Journal Issue: 2 Vol. 31; ISSN 0888-7543; ISSN GNMCEP
- Country of Publication:
- United States
- Language:
- English
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