Recent advances in laser microprobe mass analysis (LAMMA) of inner ear tissue
Maintenance of ionic gradients within the various fluids compartments of the inner ear requires transport active cellular systems at different locations. LAMMA analysis is ideally suited for detection of ions in microquantity on cellular levels overcoming many technical difficulties. The present paper summarizes the results of microprobe analysis obtained with laser induced mass spectrometry (LAMMA) supplemented by X-ray microprobe analysis of epithelial cell layers adjacent to the endolymphatic space in the cochlear duct, in the vestibular organ and in the endolymphatic sac. The possible role of inner ear as well as ocular melanin in the mechanisms of active ion transport is discussed.
- OSTI ID:
- 5016702
- Journal Information:
- Scanning Electron Microsc.; (United States), Journal Name: Scanning Electron Microsc.; (United States) Vol. 1; ISSN SEMYB
- Country of Publication:
- United States
- Language:
- English
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560400 -- Other Environmental Pollutant Effects
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL TISSUES
ANIMALS
AUDITORY ORGANS
BIOLOGICAL MATERIALS
BODY
BODY AREAS
BODY FLUIDS
CHEMICAL ANALYSIS
ELECTROLYTES
ELECTRON MICROPROBE ANALYSIS
EPITHELIUM
EYES
FACE
GUINEA PIGS
HEAD
HYDROXY COMPOUNDS
LASERS
MAMMALS
MATERIALS
MELANIN
MEMBRANE TRANSPORT
MICROANALYSIS
MOLECULAR STRUCTURE
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
PIGMENTS
RODENTS
SENSE ORGANS
TISSUES
VERTEBRATES
VESTIBULAR APPARATUS