Activity quantitation in SPECT; A comparison of three attenuation correction methods in combination with pre-reconstruction resotration filtering

Journal Article · Mon Apr 01 04:00:00 EST 1991 · IEEE Transactions on Nuclear Science (Institute of Electrical and Electronics Engineers); (United States)

DOI:https://doi.org/10.1109/23.289385· OSTI ID:5012863

King, M A; Glick, S J; Penney, B C ^[1]

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1. Massachusetts Univ., Worcester, MA (United States). Dept. of Nuclear Medicine

This paper reports on a study of activity quantitation with pre-reconstruction Metz filtering and use of arithmetic mean pre-reconstruction, Chang's post-reconstruction, or Bellini's intrinsic attenuation correction that was conducted. Tc-99m filled spheres of various diameters were used to study activity estimation within an elliptical cross-section phantom. The percent of air sensitivity, which is calculated as the count rate for an ROI per unit activity for a source in the phantom divided by the count rate per unit activity for a point source in air times 100 percent, was used to assess the accuracy of attenuation correction. It was determined that a transmission model which explicitly included the buildup of scattered radiation yielded more accurate quantitation of activity in a uniform tub than correcting for scatter by scaling the counts with an average scatter fraction. The use of 2D pre-reconstruction Metz filtering combined with Bellini's intrinsic or Chang's post-reconstruction attenuation correction resulted in percent sensitivities which were the least position dependent and closest to 100 percent.

• OSTI ID: 5012863
• Journal Information: IEEE Transactions on Nuclear Science (Institute of Electrical and Electronics Engineers); (United States), Journal Name: IEEE Transactions on Nuclear Science (Institute of Electrical and Electronics Engineers); (United States) Vol. 38:2; ISSN 0018-9499; ISSN IETNA
• Country of Publication: United States
• Language: English

Related Subjects

550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
COMPARATIVE EVALUATIONS
COMPUTERIZED TOMOGRAPHY
COUNTING RATES
DIAGNOSTIC TECHNIQUES
EMISSION COMPUTED TOMOGRAPHY
EVALUATION
IMAGE PROCESSING
MOCKUP
PHANTOMS
PROCESSING
SCATTERING
SENSITIVITY
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
STRUCTURAL MODELS
TOMOGRAPHY