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Implementation of simultaneous attenuation and detector response correction in SPECT

Conference · · IEEE Trans. Nucl. Sci.; (United States)
OSTI ID:7247429
; ; ;

Simultaneous correction of attenuation and detector response was implemented in Single Photon Emission Computed Tomography (SPECT) image reconstruction. The authors developed a ray-driven projector-backprotector which exactly models attenuation in the reconstructed image slice and the spatially variant detector response. The projector-backprotector was used in the iterative maximum likelihood algorithm to simultaneously correct for nonuniform attenuation and detector response. A computer generated heart-lung phantom was used in simulation studies to compare the simultaneous correction method with the intrinsic attenuation correction method with a smoothing filter, the intrinsic attenuation correction method with a deconvolution filter, and a modified Chang attenuation correction method which uses nonuniform attenuation distribution. The results demonstrate that the simultaneous correction method using the iterative maximum likelihood algorithm provides more accurate quantitation and superior image quality compared to the other correction techniques tested.

Research Organization:
Dept. of Radiology and Curriculum in Biomedical Engineering, The Univ. of North Carolina at Chapel Hill, CBnumber 7575, 152 MacNider Hall, Chapel Hill, NC (US)
OSTI ID:
7247429
Report Number(s):
CONF-871006-
Journal Information:
IEEE Trans. Nucl. Sci.; (United States), Journal Name: IEEE Trans. Nucl. Sci.; (United States) Vol. 35:1; ISSN IETNA
Country of Publication:
United States
Language:
English

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Related Subjects

07 ISOTOPE AND RADIATION SOURCES
440101 -- Radiation Instrumentation-- General Detectors or Monitors & Radiometric Instruments
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
61 RADIATION PROTECTION AND DOSIMETRY
655002 -- Medical Physics-- Radiation Source Calibration & Standardization
655003* -- Medical Physics-- Dosimetry
99 GENERAL AND MISCELLANEOUS
990230 -- Mathematics & Mathematical Models-- (1987-1989)
ALGORITHMS
ATTENUATION
BODY
CALCULATION METHODS
CARDIOVASCULAR SYSTEM
COMPUTER CALCULATIONS
COMPUTERIZED TOMOGRAPHY
CONTROL
CORRECTIONS
DIAGNOSTIC TECHNIQUES
DOSIMETRY
EMISSION COMPUTED TOMOGRAPHY
HEART
IMAGE PROCESSING
IMAGE SCANNERS
ITERATIVE METHODS
LUNGS
MATHEMATICAL LOGIC
MAXIMUM-LIKELIHOOD FIT
MEASURING INSTRUMENTS
MOCKUP
NUMERICAL SOLUTION
ORGANS
PHANTOMS
PROCESSING
QUALITY CONTROL
RADIATION DETECTORS
RESPIRATORY SYSTEM
SIMULATION
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
STRUCTURAL MODELS
TECHNOLOGY ASSESSMENT
TOMOGRAPHY