Effect of daily oral subtoxic doses of a wet lead-based paint on cattle

Journal Article · Thu Jan 01 04:00:00 EST 1976 · Bull. Environ. Contam. Toxicol.; (United States)

DOI:https://doi.org/10.1007/BF01685222· OSTI ID:5010743

Wright, F C; Younger, R L; Riner, J C

Cattle were dosed daily with a wet lead-based paint at a rate of about 6 mg of lead per kg per day for 60 weeks. The cattle did not exhibit overt symptoms of lead toxicosis. Blood and fecal samples collected during the study, and tissue samples obtained at slaughter of the animals were analyzed for led by atomic absorption spectrophotometer equipped with a graphite furnace. Levels of lead in whole blood generally did not exceed 0.5 ppm. The residues of lead in feces reached as high as 1000 ppm. Highest residues in tissues were in calcified bone, the kidney cortex, kidney medulla, and then in liver. Residues of lead in muscle, brain, spleen, and bone marrow were similar to residues of lead in the control animal. Calves born to 2 test animals had elevated levels of lead in bone, kidney and liver. 10 references, 2 figures, 1 table.

• Research Organization: Dept. of Agriculture, Kerrvile, TX
• OSTI ID: 5010743
• Journal Information: Bull. Environ. Contam. Toxicol.; (United States), Journal Name: Bull. Environ. Contam. Toxicol.; (United States) Vol. 16:2; ISSN BECTA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION SPECTROSCOPY
ANIMAL TISSUES
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BLOOD
BODY
BODY FLUIDS
BONE MARROW
BRAIN
CATTLE
CENTRAL NERVOUS SYSTEM
CLEARANCE
COATINGS
CONTAMINATION
DAILY VARIATIONS
DATA
DIGESTIVE SYSTEM
DISTRIBUTION
DOMESTIC ANIMALS
ELEMENTS
EXCRETION
EXPERIMENTAL DATA
FECES
GLANDS
HEMATOPOIETIC SYSTEM
INFORMATION
INGESTION
INTAKE
KIDNEYS
LEAD
LIVER
MAMMALS
MATERIALS
METALS
MUSCLES
NERVOUS SYSTEM
NUMERICAL DATA
ORGANS
PAINTS
PROGENY
RESIDUES
RUMINANTS
SKELETON
SPECTROSCOPY
SPLEEN
TISSUE DISTRIBUTION
TISSUES
VARIATIONS
VERTEBRATES
WASTES