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Decreased nucleic acid synthesis in low-dose-irradiated lymphocytes--effect of TCGF addition

Journal Article · · Radiat. Res.; (United States)
DOI:https://doi.org/10.2307/3576805· OSTI ID:5006004

Flow cytometry was used to evaluate nucleic acid synthesis in irradiated mixed lymphocyte cultures (MLC) compared to nonirradiated control cultures. Two staining methods were used (propidium iodide and acridine orange). We showed that RNA and DNA synthesis are retarded in MLC receiving 0.2 Gy. This effect was reversed by lymphocyte growth factor.

Research Organization:
INSERM, Montpellier, France
OSTI ID:
5006004
Journal Information:
Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 2; ISSN RAREA
Country of Publication:
United States
Language:
English