Benzene-RISc: The development and performance of an immunoassay to detect benzene in water
- Ensys Environmental Products, Inc., Morrisville, NC (United States)
Immunoassay methods have become available for environmental applications. Their simplicity, reliability, and ability to provide information rapidly and on-site is enhancing the efficiency of many field and laboratory programs. Immunoassay methods rely upon antibody molecules to provide the sensitivity and specificity characteristics they exhibit, but many molecules are either insufficiently immunogenic or structurally unremarkable to induce an appropriate antibody response. Such compounds are usually considered to be incompatible with the development of an immunoassay method. An immunoassay method for the detection of benzene in water would have utility in detecting contamination from spills and leaking underground storage tanks. Benzene, however, is frequently considered to be in the class of compounds considered to be incompatible with antibody, and therefore immunoassay, development. The authors have developed an immunoassay for the detection of benzene in water by developing both sample processing and immunochemical procedures and reagents that overcome the technical limitations frequently encountered.
- OSTI ID:
- 49408
- Report Number(s):
- CONF-941189-; ISBN 1-56590-016-2; TRN: IM9523%%231
- Resource Relation:
- Conference: SUPERFUND XV: 15th environmental conference and exhibition for the hazardous materials/hazardous waste management industry, Washington, DC (United States), 29 Nov - 1 Dec 1994; Other Information: PBD: 1994; Related Information: Is Part Of Superfund XV conference proceedings. Volume 1; PB: 866 p.
- Country of Publication:
- United States
- Language:
- English
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