Multagenicity of radon and radon daughters. Final technical report, January 1, 1993--December 31, 1996
The objective of this research was to investigate the dose-response relationship with regard to the lethal and mutagenic effects of exposure of cells to radon and its decay products. Dose-rate dependence was studied, as well as the nature of the DNA lesions. The effect of DNA repair on the lethal and mutagenic effects of exposure and on the character of the DNA lesions was investigated by comparing the response of L5178Y strains that differ in their ability to rejoin X radiation-induced DNA double strand breaks. The nature of radon/radon daughter-induced mutational lesions in human lymphoblasts was also investigated.
- Research Organization:
- Case Western Reserve Univ., Cleveland, OH (United States). Dept. of Radiology
- Sponsoring Organization:
- USDOE Office of Energy Research, Washington, DC (United States)
- DOE Contract Number:
- FG02-88ER60658
- OSTI ID:
- 491414
- Report Number(s):
- DOE/ER/60658--T2; ON: DE97006788
- Country of Publication:
- United States
- Language:
- English
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