THE PRODUCTION OF SUBSTANCES OF VERY HIGH BIOLOGICAL EFFICIENCY BY IRRADIATION OF AGAR WITH HIGH DOSE OUTPUTS (in German)
Journal Article
·
· Zeitschrift fuer Naturforschung (West Germany) Divided into Z. Nautrforsch., A, and Z. Naturforsch., B: Anorg. Chem., Org. Chem., Biochem., Biophys.,
OSTI ID:4838013
In an earlier work it was shown that in the preliminary irradiation of agar with x rays, alpha particles, and uv very effective inactivating substances (IS) arise, and that their formation took place in several stages (multi-hit IS). Only B. coli were used as test objects. Staph. aureus and B. subtilis were inactivated after preliminary irradiation of the agar with x rays, but not after irradiation with alpha particles or uv. It is probable or to be suspected that the IS arising in the preliminary radiation with a particles can and uv can penetrate the cell membrane of B. coli but not that of Staph. aureus and B. subtilis. If B. coli is irradiated directly on the agar with alpha particles so that the dose rate is varied, a dependence of the inactivation probability on dose rate is found. This is explained by diffusron of the multi- hit IS to the cells during irradiation. A comparative investigation of the inactivation of B. coli by direct irradiation on agar and on glass shows that in agar no one-hit IS occur-s (that is, no IS was formed by a single hit or clementary act) or at least these do not penetrate through the cell membranes of B. coli. (tr-auth)
- Research Organization:
- Universitat, Freiburg i. Br.; and Stadt. Krankenanstalte, Karlsruhe, Ger.
- NSA Number:
- NSA-16-021986
- OSTI ID:
- 4838013
- Journal Information:
- Zeitschrift fuer Naturforschung (West Germany) Divided into Z. Nautrforsch., A, and Z. Naturforsch., B: Anorg. Chem., Org. Chem., Biochem., Biophys.,, Journal Name: Zeitschrift fuer Naturforschung (West Germany) Divided into Z. Nautrforsch., A, and Z. Naturforsch., B: Anorg. Chem., Org. Chem., Biochem., Biophys., Vol. Vol: 17b; ISSN ZNTFA
- Country of Publication:
- Country unknown/Code not available
- Language:
- German
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