Silica Gel Structure and the Chromatographic Process. Effect of Pore Diameter on the Adsorption and Differential Migration of Sterol Acetates
A systematic study of six types of silica gels was undertaken to determine the role of gel pore diameter in the chromatographic resolution of sterol acetates. The gels were characterized in terms of surface area, pore volume, average pore diameter, and density. A criterion analogous to the plate concept in partition chromatography was developed for the evaluation of these silica gels in the adsorption chromatography of sterol acetates. From two independent avenues of approach it is possible to demonstrate that the utilization of surface area in the adsorptive process is dependent jointly on the average pore diameter and the molecular area of the adsorbate. The significance of the adsorbent structure in the chromatographic process is discussed.
- Research Organization:
- Argonne National Lab., Ill.
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-15-032107
- OSTI ID:
- 4835646
- Journal Information:
- Analytical Chemistry, Journal Name: Analytical Chemistry Journal Issue: 12 Vol. 33; ISSN 0003-2700
- Publisher:
- American Chemical Society (ACS)
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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