THE EFFECT OF A DEUTERON MICROBEAM ON THE MOUSE CRYSTALLINE LENS

Journal Article · Thu Feb 01 04:00:00 EST 1962 · A.M.A. Arch. Ophthalmol.

DOI:https://doi.org/10.1001/archopht.1962.00960020165010· OSTI ID:4830886

von Sallmann, L; Curtis, H J; Grimes, P

The biologic significance of the radiation injury to the lens caused by exposure to a deuteron beam 0.025 mm in diameter which simulates the ionization of a heavy primary cosmic ray particle was studied in the mouse. Doses up to 33,000 rad administered with this beam produced not more than a few point opacities in the posterior lens cortex which were seen with the biomicroscop and corresponded to Wedl's vesicular cells. A small fraction of this dose delivered through a 1 mm aperture resulted in the development of many fine lenticular opacities and later in the formation of posterior cortical cataract. It is concluded that an ionization track as small as that of a heavy primary cosmic ray particle is not expected to cause more than a few point opacities in the lens cortex when the beam passes through the germinative zone or bow area. If a few degenerate cells are formed, it is possible that they will disintegrate without leaving a biomicroscopically visible trace of damage. (auth)

• Research Organization: National Inst. of Neurological Diseases and Blindness, Bethesda, Md.
• Sponsoring Organization: USDOE
• NSA Number: NSA-16-023428
• OSTI ID: 4830886
• Report Number(s): BNL-6081
• Journal Information: A.M.A. Arch. Ophthalmol., Journal Name: A.M.A. Arch. Ophthalmol. Vol. Vol: 67
• Country of Publication: United States
• Language: English

Related Subjects

ANIMAL CELLS
BIOLOGY AND MEDICINE
CATARACTS
COSMIC RADIATION
DEUTERON BEAMS
EYES
MICE
PARTICLE TRACKS
RADIATION DOSES
RADIATION EFFECTS
RADIATION INJURIES