THE EFFECT OF CYSTEINE AND CYSTEAMINE CONCENTRATIONS ON THE INACTIVATION OF X-IRRADIATED T PHAGES

Journal Article · Mon Jan 01 04:00:00 EST 1962 · Zeitschrift fuer Naturforschung (West Germany) Divided into Z. Nautrforsch., A, and Z. Naturforsch., B: Anorg. Chem., Org. Chem., Biochem., Biophys.,

OSTI ID:4829228

Hotz, G; Mueller, A

The plaque forming ability of T1 and T2 bacteriophage was inactivated by x rays. The protective action of different concentrations of the sulfhydryl compounds cysteine and cysteamine in broth, buffer, and water was investigated. T1 and T2 showed marked differences in the amount of protective cysteine molecules necessary for the same dose reduction factor. Also the formation of phage-sulfhydryl complexes was observed in T2 but not in T1. In proteinfree solutions the inactivation of T1 can be varied with cysteamine concentration from highest sensitivity obtained in water to maximum resistance which is not changed by the addition of broth. (auth)

• Research Organization: Kernforschungszentrum, Karlsruhe, Ger.
• NSA Number: NSA-16-020293
• OSTI ID: 4829228
• Journal Information: Zeitschrift fuer Naturforschung (West Germany) Divided into Z. Nautrforsch., A, and Z. Naturforsch., B: Anorg. Chem., Org. Chem., Biochem., Biophys.,, Journal Name: Zeitschrift fuer Naturforschung (West Germany) Divided into Z. Nautrforsch., A, and Z. Naturforsch., B: Anorg. Chem., Org. Chem., Biochem., Biophys., Vol. Vol: 17b; ISSN ZNTFA
• Country of Publication: Country unknown/Code not available
• Language: German

Related Subjects

BACTERIOPHAGES
BIOLOGY AND MEDICINE
CYSTEAMINE
CYSTEINE
RADIATION PROTECTION
RADIOSENSITIVITY
WATER
X RADIATION