Protection by Inorganic Condensed Phosphates against the Lethal Effects of X-rays
Results show that sodium pyrophosphate, linear tripolyphosphate, and cyclic trimeta- and tetrametaphosphates markedly reduce the niortality in mice due to x rays when injected intraperltoneally in neutral solution, shortly before exposure. A comparison is made of trimetaphosphate and S, beta- aminoethylisothiuronium bromide hydrobromide (AET) in order to determine the highest protection given by the compounds. Results show that trimetaphosphate is significantly less protective than AET, but its lower fiducial limit, 1059 r, is well above the LD/sub 50/ of uninjected nice of this strain, which is known to be about 860 r. (N.W.R.)
- Research Organization:
- Medical Research Council, Didcot, Berks, Eng.
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-16-004069
- OSTI ID:
- 4828893
- Journal Information:
- Nature (London), Journal Name: Nature (London) Journal Issue: 4802 Vol. 192; ISSN 0028-0836
- Publisher:
- Nature Publishing Group
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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