EXPERIMENTAL STUDIES ON THE EFFECTS OF X-RAYS ON THE IMMATURE BONE

Journal Article · Fri Jan 01 04:00:00 EST 1960 · Nippon Igaku Hoshasen Gakkai Zasshi (Japan)

OSTI ID:4828303

Kuroda, Y

Dividing the tibia of 3-week-old mice into 5 parts, the variations of alkaline phosphatase activity, P/sup 32/ uptake, and their pathological changes were examined. When the tibia was damaged severely in parts of the epiphysis and metaphysis with a single x irradiation of 1000 r the recovery was slow. The retardation of bone growth increased with the dose and it was found that the tibia showed a shortening in length following a dose of 1000 r, and with a dose of over 2000 r the increase of the weight was restricted in the irradiated tibia. P3/ uptake in the tibia decreased exponentially with a dose up to 3000 r, except in parts of the metaphysis. The depression of P/sup 32/ uptake in the tibia produced by fractionated x irradiation was less than that produced by a single x irradiation in the same x-ray dose, and its manifestation varied essentially with the fractionated dose and the time interval. (Abstr. Japan Med., 1: No. 13, l961)

• Research Organization: Jikei Univ., Tokyo
• NSA Number: NSA-16-004092
• OSTI ID: 4828303
• Journal Information: Nippon Igaku Hoshasen Gakkai Zasshi (Japan), Journal Name: Nippon Igaku Hoshasen Gakkai Zasshi (Japan) Vol. Vol: 20; ISSN NHGZA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AGE
BIOLOGY AND MEDICINE
BONES
ENZYMES
METABOLISM
MICE
PHOSPHORUS 32
RADIATION DOSES
RADIATION EFFECTS
RECOVERY
TRACER TECHNIQUES
X RADIATION