THE EFFECT OF VARIOUS RADIATION PROTECTION MATERIALS ON THE RADIOSENSITIVITY OF TUMORS

Journal Article · Mon Jan 01 04:00:00 EST 1962 · Nuclear-Med.

OSTI ID:4827623

Koch, R

The influence of the agents cysteamine, serotonin, nicotinamide, thiourea, d-penicillinamine, and 5-mercaptopyridoxine on the radiosensitivity of tumor tissue in vitro and in vivo is tested. The investigations were with the mouse tumors Ehrlich ascites, solid Ehrlich carcinoma, and Crocker sarcoma l80. In the case of Ehrlich ascites only cysteamine, serotonine, and nicotinamide are able to protect the ascites cells. If solid Ehrlich carcinoma is irradiated in vivo, a significant protective action of cysteamine, serotonin, d-penicillamine, and 5-mercaptopyridoxine could be shown. In the same experiments with Crocker sarcoma none of the investigated substances are able to protect the in vivo irradiated tumor. (auth)

• Research Organization: Universitat, Freiburg i B.
• NSA Number: NSA-16-021966
• OSTI ID: 4827623
• Journal Information: Nuclear-Med., Journal Name: Nuclear-Med. Vol. Vol: 2
• Country of Publication: Country unknown/Code not available
• Language: German

Related Subjects

AMINES
ANIMAL CELLS
ANTIBIOTICS
BIOLOGY AND MEDICINE
CHEMICALS
HETEROCYCLICS
METHANOL
METHYL RADICALS
ORGANIC NITROGEN COMPOUNDS
ORGANIC SULFUR COMPOUNDS
PENICILLIN
PYRIDINES
RADIATION PROTECTION
RADIOSENSITIVITY
SEROTONIN
THIOLS
TUMORS
UREA
VITAMIN PP
VITAMINS