THE RETENTION AND TRANSLOCATION OF INHALED Pu$sup 239$$O$$sub 2$ PARTICLES
Mice exposed to Pu/sup 239/O/sub 2/ aerosols deposited about 20% of the amount inhaled in lungs. From 40 to 60% was distributed ed between the nasal and oral passages and the gastrointestinal tract. Although the major poition of the body burden was associated with the lung, during a 70 week period there was gradual translocation to the skeleton. muscle, liver, and splecn. The skeleton accumulated the largest quantity of translocated Pu/sup 239/, about 0.3% of the total dose. This was equal to the amount remaining in lung. The halflife for clearance of about four % of the Pu/sup 239/ initially deposited in the lung was 460 days. The remainder was cleared with half-lives of 20 days or less. Assuming uniform distribution after deposition of 0.02/uc Pu/sup 239/ in the lung, the total alpha dose to mouse lung tissue during the 70 week period was 550 rad. (auth)
- Research Organization:
- General Electric Co., Richland, Wash.
- NSA Number:
- NSA-16-026714
- OSTI ID:
- 4822434
- Report Number(s):
- HW-SA-1989
- Journal Information:
- Trans. Am. Nuclear Soc., Journal Name: Trans. Am. Nuclear Soc. Vol. Vol: 3
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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