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THE FEATURES OF THE COURSE OF CERTAIN AILMENTS OF THE INTERNAL ORGANS AGAINST A BACKGROUND OF RADIATION AFFLICTIONS

Journal Article · · Voenno-Med. Zhur.
OSTI ID:4798446

In view of the absence of published information on changes in the clinical course of internal diseases as a result of radiation ailments, the course of certain diseases was studied against a background of radiation sickness. The results of a study of experimental exudative pleuritis and myocarditis complicated by acute radiation sickness are presented. Exudative pleuritis in rabbits was studied: without radiation sickness, with radiation sickness but without pleuritis, and with pleuritis evoked immediately after irradiation and 7 dnys after irradiation. The total radiation dose was 502 r. It was found that exudative pleuritis complicated by radiation sickness had a number of features peculiar only to the combined ailment: marked and rapid development of anemia; stormy course of pleuritis of a definite hemorrhagic nature; the formation of extensive blood clots in the pleural cavity; considerable retardation of exudate resorption; complication by pneumonia; high mortality. The disease was most severe in cases where pleuritis was evoked at the height of radiation sickness. The experimental myocarditis tests were conducted in a similar manner. The course of myocarditis in the irradiated animals (as compared with the intact rabbits) was much more severe, often with progressive leukopenia (usually accompanied by lymphopenia) and a high mortality rate (11 out of 17 animals). The myocardium seemed to be affected earlier and more deeply than in the intact animals. The results show that radiation gives pleuritis and myocarditis features that are not typical of the pathological process in non-irradiated animals. (OTS)

Research Organization:
Originating Research Org. not identified
NSA Number:
NSA-16-014607
OSTI ID:
4798446
Journal Information:
Voenno-Med. Zhur., Journal Name: Voenno-Med. Zhur. Vol. Vol: No. 7
Country of Publication:
Country unknown/Code not available
Language:
English

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