Effect of Selenium on Methionine Formation in vivo and in vitro
Journal Article
·
· Experimental Biology and Medicine
The effect of chronic selenosis on methionine and cystine content in liver of experimental animals was studied. The decrease in methionine in chronic selenosis was not associated with restricted food intake and sub sequent starvation. In in vitro experiments, using rat liver homogenate, sodium selenate and selenite inhibited transmethylation reactions of homocystine and homocysteine by betaine and choline. Selenite was a more active biological inhibitor than selenate. The significance of the results was discussed with reference to the detoxification mechanism in selenium poisoning in animals.
- Research Organization:
- Univ. of Wyoming, Laramie
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-16-014442
- OSTI ID:
- 4795183
- Journal Information:
- Experimental Biology and Medicine, Journal Name: Experimental Biology and Medicine Journal Issue: 3 Vol. 109; ISSN 1535-3702
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
Similar Records
Methionine kinetics in adult men: effects of dietary betaine on L-(2H3-methyl-1-13C)methionine
Comparative toxicity of selenate, selenite, seleno-DL-methionine and seleno-DL-cystine to Daphnia magna
Synthesis of Methionine in X-irradiated Rats
Journal Article
·
Thu Aug 01 00:00:00 EDT 1991
· American Journal of Clinical Nutrition; (United States)
·
OSTI ID:5393006
Comparative toxicity of selenate, selenite, seleno-DL-methionine and seleno-DL-cystine to Daphnia magna
Journal Article
·
Wed Mar 31 23:00:00 EST 1993
· Environmental Toxicology and Chemistry; (United States)
·
OSTI ID:6773707
Synthesis of Methionine in X-irradiated Rats
Journal Article
·
Sun Dec 31 23:00:00 EST 1961
· International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine
·
OSTI ID:4785277