DEVELOPMENT OF CHICK EMBRYO GONADS GRAFTED IN A HOST EMBRYO AFTER TREATMENT IN CULTURE BY X RAYS

Journal Article · Sun Jan 01 04:00:00 EST 1961 · Acta Anatomica (Switzerland)

OSTI ID:4791949

Salzgeber, B

Cultures of chick embryo ovary and testis were irradiated with 1600 to 12,450 r, transplanted to the coelom of young embryos after various intervals, and allowed to develop for 10 to 12 days. Some grafts degenerated; others developed abnormally. The ovarian cortex was particularly sensitive and usually underwent destruction. In some instances the irradiated ovary was reduced entirely to medullary constituents enclosed by large lacunar structures. The seminiferous tubules of testis became disorganized. Endocrine activity of irradiated, transplanted gonads was assessed by their effect on genital structures of the host embryo. Male and female gonads showed differences in sensitivity of their endocrine cells to irradiation. Irradiated ovaries retained their hormonal activity and, as in controls, caused feminization of male host embryo. In contrast, testes submitted to high doses of radiation showed impaired hormone secretion as seen by their inability to cause regression if Mullerian duct in female host embryos. (H.H.D.)

• Research Organization: College de France, Nogent
• NSA Number: NSA-16-028758
• OSTI ID: 4791949
• Journal Information: Acta Anatomica (Switzerland), Journal Name: Acta Anatomica (Switzerland) Vol. Vol: 47; ISSN ACATA
• Country of Publication: Country unknown/Code not available
• Language: French

Related Subjects

ANIMAL CELLS
BIOLOGY AND MEDICINE
BIRDS
CYTOLOGY
EMBRYOS
GONADS
HORMONES
MICROSCOPY
RADIATION DOSES
RADIOSENSITIVITY
TRANSPLANTS
X RADIATION