THE DETERMINATION OF SODIUM AND POTASSIUM IN BIOLOGICAL MATERIAL BY NEUTRON ACTIVATION ANALYSIS

Journal Article · Mon Jan 01 04:00:00 EST 1962 · Clinica Chimica Acta (Netherlands)

DOI:https://doi.org/10.1016/0009-8981(62)90109-2· OSTI ID:4786912

Pijck, J; Hoste, J

Two procedures for the determination of sodium and potassium in biological fluids, by radioactivation analysis, were developed. In the chemical separation technique, samples of the order of 1 mu l were irradiated in silica capillaries. Sodium was measured selectively by gamma counting with energy discrimination, whereas potassium was separated as its dipicrylamine- or tetraphenylboron salt and counted with a G. M. tube. The method was tested on solutions of known content and applied to human blood sodium. Reproducibility proved to be better than 5% for sodium and better than 10% for potassium. When samples of the order of 10 mu l were available, the determination of both elements was possible without chemical separation. Samples and standard solutions were applied on a paper strip and irradiated. Direct and specific gamma -counting of the sodium and beta -counting of the potassium isotopes is then possible with a reproducibility generally better than 10%. (auth)

• Research Organization: Universiteit, Ghent
• NSA Number: NSA-16-012985
• OSTI ID: 4786912
• Journal Information: Clinica Chimica Acta (Netherlands), Journal Name: Clinica Chimica Acta (Netherlands) Vol. Vol: 7; ISSN CCATA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ACTIVATION ANALYSIS
AMINES
BETA DETECTION
BLOOD SERUM
BORON COMPOUNDS
CAPILLARIES
CHEMISTRY
GAMMA DETECTION
GEIGER-MUELLER COUNTERS
MAN
NEUTRONS
PHENYL RADICALS
PICRYL RADICALS
POTASSIUM COMPLEXES
QUANTITATIVE ANALYSIS
SEPARATION PROCESSES
SILICON OXIDES
SODIUM
TRACE AMOUNTS