REMOVAL OF RADIOSTRONTIUM IN MAN BY ORALLY ADMINISTERED AMMONIUM CHLORIDE TWO WEEKS AFTER EXPOSURE: THE EFFECT OF LOW AND HIGH CALCIUM INTAKE
The removal of radiostrontium was studied in man by means of orally administered ammonium chloride during low and high calcium intake both at the time of the injection of the Sr/sup 85/ tracer and two weeks thereafter. During low calcium intake, orally administered ammonium chloride was as effective in removing radiostrontium two weeks after administration of the tracer as at the time of the injection of the tracer. Ammonium chloride given in the late phase during high calcium intake was less effective than in the same phase during low calcium intake, due to the higher urinary excretion of calcium and of radiostrontium prior to the administration of ammonium chloride during high calcium intake. Two weeks after exposure, the Sr/sup 85/ body burden was approximately twice as high in patients maintained on low calcium intake as in those receiving calcium supplements. The excess radiostrontium excretion induced by ammonium chloride was approximately twice as high in terms of the retained dose in the former as in the latter group. (auth)
- Research Organization:
- Montefiore Hospital, New York
- NSA Number:
- NSA-17-001213
- OSTI ID:
- 4774230
- Report Number(s):
- TID-6738; 0009-0360
- Journal Information:
- Clinical Science (England) Changed to Clin. Sci. Mol. Med., Journal Name: Clinical Science (England) Changed to Clin. Sci. Mol. Med. Vol. Vol: 20; ISSN CSCIA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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