THE EFFECT OF TOTAL-BODY X-IRRADIATION ON SERUM PROTEINS IN THE HAMSTER

Journal Article · Wed Oct 31 23:00:00 EST 1962 · Radiation Res.

DOI:https://doi.org/10.2307/3571217· OSTI ID:4773115

Ditzel, J

>Golden hamsters were given a single dose of either 1500 or 1000 r of whole-body x irradiation. Paper electrophoretic fractionation of the serum proteins and microscopic observations of the microcirculation in the cheek pouch were made prior to and after irradiation. After 1500 r as well as after 1000 r of whole-body x irradiation the albumin fraction decreased, and the alpha /sub 1/ -, alpha /sub 2/-, and BETA globulin fractions increased. A correlation was found between the degree of intravascular erythrocyte aggregation observed in the microcirculation of the cheek pouch and the decrease in the albumin/globulin ratio. This supports the concept that the phenomenon of sludging in vivo is governed by the same forces as those governing rouleaux formation in vitro. (auth)

• Research Organization: Boston Univ.; New England Deaconess Hospital, Boston; and Harvard Medical School, Boston
• Sponsoring Organization: USDOE
• NSA Number: NSA-17-001318
• OSTI ID: 4773115
• Journal Information: Radiation Res., Journal Name: Radiation Res. Vol. Vol: 17
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ALBUMINS
ANIMALS
BIOLOGY AND MEDICINE
BLOOD SERUM
BLOOD VESSELS
BODY
CALCIUM
COMPLEXES
ELECTROLYSIS
ELECTROPHORESIS
ERYTHROCYTES
EUTECTICS
GLOBULINS
HAMSTERS
HIGH TEMPERATURE
IMPURITIES
IONS
IRON
LITHIUM CHLORIDES
MELTING
METALS
MICROSCOPY
MIXING
POTASSIUM CHLORIDES
PRECIPITATION
PROTEINS
QUANTITY RATIO
RADIATION DOSES
RADIATION EFFECTS
REDUCTION
SODIUM FLUORIDES
SOLUTIONS
TISSUES
URANIUM
URANIUM FLUORIDES
URANYL NITRATES
X RADIATION